I am sure that Lanza, Mickunas, Rabin, and Bill Caldwell are all as excited as I am considering
the events that will be unfolding in the coming months.
Last night, I spent many hours going back over our patents, published materials, conference presentations,
videos, and comments on a very specific topic. And, this is the engraftment of the RPE Cells on the BM.
I was looking at the characteristics of the RPE Cell surfaces, the influence of integrin, and the age and the health of the BM... all, and everything and as much studies/trial information in animals and humans, as these influence the engraftment process of the RPE Cells into the BM.
This is the heart of ACTC's trials.
This morning and most of today, I am still looking for any negative data that will make me doubt or change my mind in regards to my confidence that ACTC will be successful.
Off course, I know that anything can go wrong!
On the other hand, if there is any team, anywhere, who knows this issue... It is Lanza's team.
But, I want to make sure... for my own peace of mind.
So, I reviewed our RPE patents, and Wow! Many times, and this patent is worth much much more than
one can imagine. Reviewed, again, the pre-clinical studies and animal models, reviewed other studies involving cadaver RPEs, fetal RPEs, and adult RPEs... and its engraftment results and issues...
And hell! after many hours... I still could not find any data that will dampen my judgement call that ACTC is very close to a home run.
And yes, if there are any PHDs around who will tell me that something can still go wrong... I agree.
But heck, anything can go wrong on anything, any day... but I am not talking about this kind
of statistical probability.
I just had a very nice Reserva Chianti from Tuscany and a double cappuccino...
and I am mellow.
I suppose I have done looking at all the possible things that can go wrong... and I am ok.
I am happy.
Best and just making sure,